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Classification of Anti-Cancer Drugs. • Alkylating Agents: Cyclophosphamide, Melphelan, Nitrosourea,. Platinum analogs: Cisplatin, Carboplatin. • Antimetabolites: Cytarabine, Fludarabine, Methotrexate. • Plant alkaloids: Camptothecins, Etoposide, Paclitaxel, Vinblastine. • Antitumor antibiotics: Bleomycin, Doxorubicin,
Cancer cells have lost the normal regulatory mechanisms that control cell growth and multiplication. • Cancer cell have lost their ability to differentiate (that means to specialize). • Benign cancer cell stay at the same place. • Malignant cancer cells invade new tissues to set up secondary tumors, a process known as
30 Jan 2006 Cancer drugs can be divided into two general classes: CELL CYCLE SPECIFIC. DRUGS (CCS; esp. plant alkaloids and antimetabolites), and CELL CYCLE. NON-SPECIFIC DRUGS (CCNS; esp. alkylating agents and some natural products). Antineoplastic agents can also be organized according to their.
ANTI-TUMOUR TREATMENT. Classification of anticancer drugs—a new system based on therapeutic targets. Enrique Espinosa, Pilar Zamora, Jaime Feliu and. Manuel Gonza?lez Baro?n. Servicio de Oncolog?a Me?dica, Hospital La Paz, Madrid, Spain. The arrival of a great number of new antineoplastic agents has made it
search for active drugs. Growth factors and their receptors, intracellular metabolic pathways, pro-angiogenic molecules and many more have become potential targets. We herein propose a classification of anticancer drugs based on the target. Drug may act at different levels: cancer cells, endothelium, extracellular matrix,
into these two major classes are summarized in Table 55–1. Table 55–1. Cell Cycle Effects of Major Classes of Anticancer Drugs. Cell Cycle-Specific (CCS) Agents Cell Cycle-Nonspecific (CCNS) Agents. Antimetabolites. Alkylating agents. Capecitabine. Busulfan. Cladribine. Carmustine. Cytarabine. Cyclophosphamide.
The Classification of. Anticancer Drugs. A) According. According to chemical structure structure. E g. Alkylating Agents. Antimetabolite. E.g., Alkylating Agents, Antimetabolite,. Antibiotics,. Antibiotics, Plant Extracts , Hormones ,. Others. Cont.
3 Aug 2015 This supporting document sets out a list of drugs expected to be covered during core clinical oncology training and which may be included in the clinical pharmacology module of the. First FRCR examination. It is anticipated that List A contains drugs from all the major classes. Trainees are expected to
A single colonogenic malignant cell is capable of producing progeny that can kill the host therefore ALL MALIGNANT CELLS. MUST BE KILLED OR REMOVED. ? Drugs kill cancer cells by first order kinetics
Mechanisms of anticancer drugs. SARAH PAYNE AND DAVID MILES. Introduction. 34. Principles of chemotherapy. 34. Principles of tumour biology. 34. Classification of chemotherapeutic agents. 37. Limitations of cytotoxic agents. 40. Chemotherapy in head and neck cancer. 40. Choice of chemotherapy in head and neck

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February 2018