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3 Jan 2017 alized patient-specific organoid proteome profile can be related to the . based on the mutation profile of the most common tumor driver genes in CRC .. (C) The ratio between tumor and healthy organoids found at the transcriptome and proteome levels for the different patients is shown. *To be in line with
29 Sep 2014 For identifying candidate driver genes for therapeutic target discovery and functional elucidation, knowledge of mRNA and protein correlation is critical. The vast amount of data generated by microarray and the NGSRNA-sequencing technology can be reduced to a manageable number of putative targets
Proteome-wide acetylation dynamics in human cells. Yekaterina Kori1, Simone Sidoli1, Zuo-Fei Yuan 1, Peder J. Lund1, Xiaolu Zhao2 &. Benjamin A. Garcia1. Protein acetylation plays a critical role in biological processes by regulating the functions and properties of proteins. Thus, the study of protein acetylation dynamics
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23 Jan 2015 Tissue-based map of the human proteome. Mathias Uhlen,* Linn Fagerberg, Bjorn M. Hallstrom, Cecilia Lindskog, Per Oksvold,. Adil Mardinoglu, Asa . Resolving the molecular details of proteome variation in the different tissues and organs of as cancer driver genes across 12 tumor types (29);.
Therefore we investigated untreated and inflammatory activated primary human PBMCs by proteome profiling using a 'top down' 2D-PAGE approach in addition (1.2M, pdf). Supplementary Table S1: Proteins identified in untreated (con) and inflammatory activated (act) PBMCs by shotgun proteomics. Nine independent
20 Nov 2014 While currently available information is highly biased and only covers a relatively small portion of the proteome, our systematic map appears strikingly more homogeneous, revealing a “broader" human interactome network than currently appreciated. The map also uncovers significant interconnectivity
the proteome and how these dynamics differ for individual cells l Observe ~1000 proteins in individual cells over time (not all at once): localization and level l Correlate change in location and level to cellular events. Create PDF with GO2PDF for free, if you wish to remove this line, click here to buy Virtual PDF Printer
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The HuProt™ human proteome microarray v3.1 contains. >20,000 unique, newly the human proteome; see figure, right) and 124 unique mouse Piezoelectric Printer. Spot Morphology: The piezoelectric “inkjet" process allows the rapid produc- tion of high quality microarray slides time after time, with improved accuracy.
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