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SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) is a placebo-controlled, randomized clinical trial sponsored by the National Heart Lung and Blood Institute of the National Institutes of Health (NIH) to study the use of implantable cardioverter defibrillators (ICDs) in heart failure patients with poor cardiac pumping
13 Jun 2014 Design. Multicenter, double-blinded, parallel-group, randomized, placebo-controlled trial; N="2",521. Amiodarone (n=845); Shock-only ICD (n=829); Placebo (n=847). Enrollment: 1997-2001; Median follow up: 45.5 months; Primary outcome: All-cause mortality
11 Jul 2006 Background—In the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT), implantable cardioverter-defibrillator. (ICD) therapy significantly reduced all-cause mortality rates compared with medical therapy alone in patients with stable, moderately symptomatic heart failure, whereas amiodarone had no
Patient Initials: ____ ____ ____ Patient Study #: ____ ____ ____—____ ____ ____ Date of Randomization: ____/____/____ mo day yr. Sudden Cardiac Death. Baseline Case Report Form. SCD HeFT. Heart Failure Trial. DEMOGRAPHICS. Date of birth: _____/_____/_____ mo day yr. Gender: ? Male. ? Female.
1 Feb 2018 tests to identify subjects, the study is designed to facilitate ease of enrollment and to be broadly applicable as a primary prevention strategy implemented on an outpatient basis. The study will carry the acronym of SCD-HeFT, for Sudden Cardiac Death in Heart Failure: Trial of prophylactic amiodarone or.
To compare conventional treatment of congestive heart failure (CHF) with two experimental interventions: amiodarone and an implantable cardioverter-defibrillator (ICD). Condition or disease, Intervention/treatment, Phase. Arrhythmia Cardiovascular Diseases Death, Sudden, Cardiac Heart Diseases Heart Failure,
16 Apr 2004 Sudden cardiac death (SCD) is the leading cause of death in the United States and in most developed nations. Patients with impaired left ventricular function and congestive heart failure (CHF) are most susceptible to SCD, with a risk 6-9 times that in the general population. Antiarrhythmic drug therapy
15 Oct 2007 With the exception of the. SCD-HeFT (Sudden Cardiac Death Heart Failure Trial). (4), CASH (Cardiac Arrest Study Hamburg) (5), and. MUSTT (Multicenter Unsustained Ventricular Tachycar- dia Trial) studies (6), the patients in ICD trials randomized to the “control" arm received antiarrhythmic drug therapy.
20 Jan 2005 The Sudden Cardiac Death in Heart Failure Trial. (SCD-HeFT)11 was designed to evaluate the hy- pothesis that amiodarone or a conservatively pro- grammed shock-only, single-lead ICD would de- crease the risk of death from any cause in a broad population of patients with mild-to-moderate heart failure.
Background: Sudden Cardiac Death Heart Failure Trial (SCD-HeFT) began in 1997 and remains the only placebo-controlled implantable cardioverter-defibrillator (ICD) trial, testing amiodarone vs placebo and single-lead shock-only ICD therapy vs placebo for the prevention of death in congestive heart failure. A total of
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