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26 May 2015 References: Case report: Wong, Jin Shyan, Hock-Hin Chua, Clare Tan, and Teng-Aik Ong. “Acute Anuric Renal Failure Following Jering Bean Ingestion." Asian Journal of Surgery 30.1 (2007): 80-81. First synthesis (free PDF): du Vigneaud, Vincent and Patterson, Wilbur I. “The Synthesis of Djenkolic Acid.
Physiochemical Properties. • Boiling, frying, roasting the djenkol bean does not prevent toxicity. • Pungent smell in the breath. • Characteristic urine is sulfuric odor metabolizing toxic product. - difference in the djenkolic acid content H'ng PK, Nayar SK, Lau WM, Segasothy M. Acute renal failure following Jering ingestion.
Djenkolic acid (or sometimes jengkolic acid) is a sulfur-containing non-protein amino acid naturally found in djenkol beans of the South-East Asian legumes jengkol (Archidendron jiringa). The toxin consists of two cysteine radicals connected by a single carbon between the sulfur atoms. It is toxic to humans, often causing
substances and acute kidney injury is a common and important manifestation of their toxicity. The most usual .. djenkolic acid. (C11H23N3S3O6), a sulfur-rich cysteine thioacetal of formaldehyde. It forms needle-like crystals at high concentrations and a low pH. They can precipitate .. Medicine_A_Worldwide_Review.pdf.
Based on its chemistry, djenkoi bean-associated acute renal failure may be analogous to acute uric acid nephropathy. 0 fSR5 by the National Kidney Foundation, Inc. - INDEX WORDS: Djenkoiism; acute renal failure. A CUTE renal failure following ingestion of djenkol (jering) beans (Pithecolobium Zo- baturn, family
D j enkolic Acid. Curiously enough the djenkolic acid was first isolated from the urine of natives of Java who had eaten the djenkol bean and were suffering from ingestion. Apparently individuals differ greatly in their sensitiv- ity, some becoming sick after eating as little as one-half of a bean weighing about 15 gm., while
16 Apr 2014 The precise pathogenesis of acute kidney injury following djenkol ingestion remains unknown. However, it is proposed that an interaction between the characteristics of the ingested beans and the host factors causes hypersaturation of djenkolic acid crystals within the urinary system, resulting in
23 Jul 2009 Common Name, Djenkolic acid. Class, Small Molecule. Description, Djenkolic acid is a plant toxin found in the beans of the South-East Asian legumes jengkol (Archidendron jiringa). It is nephrotoxic to humans. (1). Compound Type. Amine; Ether; Natural Compound; Organic Compound; Plant Toxin.
djenkolic acid, a sulfur-containing amino acid.3 Djenkolism or jering poisoning has been shown to cause mild to severe acute tubular obstruction with some glomerular cell necrosis.3 Cases of jering nephropathy have been reported sporadically.4–8. The urine and breath of the affected individual usually have a pungent
23 Dec 2010 In this case, P. jiringa contains djenkolic acid which is a type of amino acid and sulphur that are able to kill and inhibit pests [4]. The acid has been suggested to form needle-like crystals in the urine after ingestion and have the ability to cut renal tissue which may lead to bleeding and obstruction in kidney [5].

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March 2018