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Tests that seek to assay known cancer driver genes or hotspots typically aim for high sensitivity to call these specific variants and are less concerned with novel or false positive incidental events. To achieve acceptable sensitivity (>99 %) for clinical use in solid tumor fresh
6 Oct 2017 The Personalis ACE CancerPlus™ Test is a comprehensive genomic testing solution that provides physicians a clinical report on the genetic alterations found in cancer genes of medical importance. We use our proprietary ACE Technology platform to provide high accuracy, clinical-grade next-generation
15 Oct 2013
The mutation pattern can change as the cancer progresses and additional mutations can emerge.6,7 As current and future clinical trials mature, gene mutation results will help guide diagnosis, assess prognosis, and/or define treatment strategy for a patient (ie, become actionable). This OncoVantage test utilizes NGS to
8 Jun 2017 Guardant Health is one of the best-known tumor profiling companies that uses blood biopsies (Guardant360® test). But other DNA testing companies, such as Trovagene, utilize both blood and urine biopsies. Foundation Medicine offers profiling tests that can use either a solid biopsy or liquid biopsy.
Overview. Too often, men and women hear the words “prostate cancer," “breast cancer," and “colorectal cancer" from their doctor and they immediately think the worst. However, many times the aggressive therapies that they are offered or demand are unnecessary—and there are now genomic-based tests that can make
Foundation Medicine® tests for solid tumor cancers are generally used for more advanced disease whereas Foundation Medicine tests for hematologic malignancies and soft tissue sarcomas can also be used at diagnosis, for prognostication, and to guide overall clinical management. Talk with your doctor to see if our tests
21 Dec 2017 One of the tests, FoundationOne CDx (F1CDx), can be used as a companion diagnostic for some cancer therapies. CDx (F1CDx) genomic test, which can identify cancer-associated alterations in 324 genes and two types of genomic alterations—called genomic signatures—in any type of solid tumor.
8 Feb 2016 Alterations in genes encoding cellular signaling molecules, especially protein kinases, can result in cancers. Drugs targeting mutant kinases are efficacious in cancer patients. The sensitivity of such drugs is related to the genetic makeup of individual tumors. Thus, mutational profiles of tumor DNA help
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