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13 Aug 2004 Lecture 1: Basics of Molecular Biology - August 13, 2004. Lecturer: Wing-Kin Sung. Scribe: Lee Yew Kok, Erwin Tantoso. 1.1 Brief history of Bioinformatics. In 1866, Gregor Johann Mendel discovered genetics. Mendel's hybridization ex- periments on peas unveiled some biological elements called genes,
The crucial insight of molecular biology is that hereditary information is passed between generations in a form that is truly, not metaphorically, digital. Understanding how that digital code directs the creation of life is the goal of molecular biology. Origins of Molecular Biology. Phenotype. Genes. Proteins. Classical Genetics.
BASICS ON MOLECULAR BIOLOGY. ? Cell – DNA – RNA – protein. ? Sequencing methods. ? arising questions for handling the data, making sense of it. ? next two week lectures: sequence alignment and genome assembly
The "RNA World". – Hypothesis: RNA preceded proteins and DNA as a primordial, information-bearing, catalytic molecule. – Assumptions: Heredity, uniformitarianism. – Predictions: • Conserved roles for RNA in fundamental machinery of life. • At least some RNAs should demonstrate elementary catalytic activity. • Role for
6 Sep 2013 Free Molecular biology lecture notes pdf BIOCHEMISTRY. 1. LECTURE NOTES ON MOLECULAR BIOLOGY Lecture notes on DNA replication, Transcription and Translation Vijay Marakala; 2. 1 Definition Prokaryotic replication Semiconservative mechanism Basic requirements - Substrates - Template
1 Introduction to Molecular Biology. Cells are fundamental building blocks of living organisms. Cells contain a nucleus, mito- chondria and chloroplasts, endoplasmatic reticulum, ribosomes, vacuoles, etc. The nucleus is important organelle because it houses chromosomes which include the DNA. The DNA is in essence a

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February 2018