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AMBR User Manual v4.3.1 - Free download as PDF File (.pdf), Text File (.txt) or read online for free.
ambr micro bioreactor vessel. A novel, disposable microscale bioreactor that mimics the characteristics of a classical laboratory scale bioreactor: • pH and DO sensor spots for continuous monitoring and control. • Integral impeller for rapid, efficient cell mixing. • Sparge tube delivers gas to the impeller mixing zone.
extremely difficult to achieve using manually-controlled shake flasks or bench top vessels without investing significant time and resources, as well as risking introducing variability into the results. Process scale-up. For early process development, the ambr15 system is suitable as a mimic of bench top bioreactor conditions.
ambr 15 single well plates are ideal for media filling during experiment setup. The large volume reduces the manual pipetting work and is ideal for experiments using a single media type. Pack contains 25 sterile plates with lids, individually wrapped. Working volume 240 mL per well, 1 well per plate. Replacement culture
27 Mar 2012 The newly developed advanced microscale bioreactor (ambr™) system uses 24 or 48 single-use, pre-sterilized, stirred-tank bioreactors on an .. The ambr™ workstation also reduced manual operations by automating liquid additions such as bolus nutrient feeds and glucose feeds, and sampling for off-line
ambr® 15 cell culture mimics the characteristics of classical bioreactors at microscale (10-15ml), by using cost effective, disposable micro bioreactors, controlled by an automated workstation. The system enables the rapid evaluation of multiple bioreactor cultures at microscale, increasing productivity in cell line development
intensified/continuous cell culture processes, however this approach is manually intensive, relatively low throughput and cost-intensive to operate. In the last 5 years, fed-batch cell culture process development has been significantly accelerated by wide spread implementation of the ambr 15 and ambr 250 fully automated,
The analysis module provides add-on capability for measurement of pH in ambr 15 micro bioreactors, for the purpose of initial bioreactor vessel pH sensor calibration and subsequent in-process re-calibration. The analysis module eliminates the operator time needed for manual pH sample transfer, measurement, data
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