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Mar 11, 2014 In a recent press release, the Society for Maternal-Fetal Medicine (SMFM) offered comments on the emerging use of noninvasive prenatal testing, concluding that recent research is not yet sufficient to change current practice recommendations from SMFM or the American Congress of Obstetricians and
The purpose of this statement is to clarify that SMFM does not recommend that cfDNA aneuploidy screening be offered to all pregnant women, nor does it suggest a requirement for insurance coverage for cfDNA screening in women at low-risk of aneuploidy. However, SMFM believes due to the ethics of patient autonomy
Jun 29, 2015 A long anticipated joint statement regarding noninvasive prenatal testing (NIPT) from The American College of Obstetricians and Gynecologists (ACOG) and SMFM is now available, Committee Opinion #640 Cell-free DNA Screening for Fetal Aneuploidy. It is thorough and provides the guidance that many
Committee on Genetics Society for Maternal–Fetal Medicine This document reflects emerging clinical and scientific advances as of the date issued and is subject to change. The information should not be construed as dictating an exclusive course of treatment or procedure to be followed. PDF Format
Jul 28, 2016 American College of Medical Genetics and Genomics (ACMG) guidelines and statements have assisted patients seeking pre- natal screening information and health-care providers respon- sible for providing accurate and up-to-date information to their patients.1–3 Until recently, noninvasive prenatal
Mar 1, 2016 These guidelines should not be construed as dictating an exclusive course of treatment or procedure. Variations Prenatal aneuploidy screening using cell-free DNA. SMFM Consult Series No. 36. Society for Maternal-Fetal. Medicine (SMFM). Am J Obstet Gynecol 2015;212:711–6. (Level III). 42. Norton
Mar 1, 2016 Regarding prenatal diagnostic testing, Mary E. Norton MD, SMFM President, and lead author of "Prenatal Diagnostic Testing for Genetic Disorders," added, "It is important to note that diagnostic testing is safe and should be an option for all women." Practice Bulletins "Screening for Fetal Aneuploidy" and
Feb 2, 2017 SUMMARY: SMFM has released, as part of their Consult Series, a document on the role of prenatal ultrasound in the context of cfDNA screening. The summary recommendations are as follows: Negative cfDNA at 11-14 weeks: (evidence level 1B). NT measurement not recommended. Negative cfDNA and
Noninvasive that uses cell-free DNA prenatal offers tremendous potential as a screening method for fetal aneuploidy. Patients who are undergoing cell-free DNA screening should be offered maternal serum alpha-fetoprotein screening or ultrasound evaluation for risk assessment. A negative cell-free DNA test result does
Maternal serum cell free DNA screening, or noninvasive prenatal testing (NIPT) for aneuploidy, uses cell free DNA from maternal serum to screen for common fetal aneuploidies with high sensitivity and specificity. NIPT uses next generation sequencing to directly measure fetal DNA in the maternal circulation, and clinical

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March 2018