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The PFA-100® provides a simple global measure of high shear- dependent platelet function, and as such is not diagnostic or specific to any disorder. Prolonged closure times must be interpreted in conjunction with a full blood count, von. Willebrand factor (VWF) screen and other platelet tests. The. PFA-100® may also give
Measuring channel, Single measuring channel. Incubation category, Two incubation wells. Incubation temperature, 37.9 °C ± 1.0 °C. Incubation warm up-time, <15 minutes (room to operating temperature). Sample Handling. Type of sample, Citrated whole blood. Sample mechanism, Manual pipette dispensing (800 ?L).
The PFA-100 is a platelet function analyser that aspirates blood in vitro from a blood specimen into disposable test cartridges through a microscopic aperture cut into a biologically active membrane at the end of a capillary. The membrane of the cartridges are coated with collagen and adenosine diphosphate (ADP) or
The platelet function analyzer PFA-100® System (Siemens Healthcare Diagnostics) has become a useful tool to detect abnormalities of primary hemostasis in small samples of blood. This test system is a microprocessor controlled instrument which emulates in vitro the platelet dependent phase of primary hemostasis, while
Background: The platelet function analyzer (PFA-100®) is a bedside test of coagulation designed to evaluate plate- let function. It measures the time required for whole blood to occlude a membrane impregnated with either epineph- rine (EPI) or adenosine 50diphosphate (ADP). The results are reported as closure time
Siemens Healthineers' PFA-100 System. The PFA-100 System measures the complex process of primary hemostasis and aids in the rapid detection of platelet dysfunction. Helps detect inherited, acquired and drug-induced platelet dysfunction.
The last results could also arise from a reduced platelet count or hematocrit. In addition to sets of test challenge tubes, participants were provided with detailed instructions and comprehensive result. Fig. 1. (A) PFA-100® CT data (seconds, y-axes) for both C/ADP and C/Epi, for sample replicated test challenges used across
The PFA-100 is a whole blood, point-of-care, platelet aggregometer that functions by aspirating a blood sample through a capillary tube at a high shear rate and . Philip Lanzkowsky M.B., Ch.B., M.D., Sc.D. (honoris causa), F.R.C.P., D.C.H., F.A.A.P., in Manual of Pediatric Hematology and Oncology (Fifth Edition), 2011
The PFA-100® System measures the complex process of primary hemostasis and aids in the rapid detection of platelet dysfunction. The PFA-100 System provides automated assessment for inherited, acquired, or drug-induced platelet dysfunction. Lippi G, Manzato F, Franchini M, et al
510(k) SUBSTANTIAL EQUIVALENCE DETERMINATION. DECISION SUMMARY. ASSAY AND INSTRUMENT COMBINATION TEMPLATE. A. 510(k) Number: K060489. B. Purpose for Submission: To obtain a change in indications for the Dade. ®. PFA-100. ®. Platelet Function Analyzer and. Dade. ®. PFA-100. ®.
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