guid eline. EURL. ECVAM. DB-ALM protocol number. Skin sensitisation. 2015 . Information obtained from similar substances having e.g. LLNA data may help in assessing the skin sensitisation potential. The OECD. QSAR Toolbox can be
Sep 27, 2016 (VUMC). PBMDC. (Beiersdorf). Modified from Reisinger et al., Toxicol in Vitro 29:259-70, 2015. PPRA (P&G). Kasting's model. SenCee Tox (CeeTox)). mMUSST (BASF). VITOSENS (VITO). SENS-IS. (Immunosearch). SensiDerm. (Proteome Sci.) LLNA. (OECD 429)Buehler, GPMT. (OECD 406). HRIPT
406. Adopted: 17.07.92. OECD GUIDELINE FOR TESTING OF CHEMICALS. Adopted by the Council on 17th July 1992. Skin Sensitisation. INTRODUCTION. 1. OECD Guidelines for Testing of The mouse ear swelling test (MEST) and the local lymph node assay (LLNA) appear to be promising. Both assays have
Jul 22, 2010 This Test Guideline is designed for assessing skin sensitization potential of chemicals in animals. TG 406 utilises guinea pig tests, notably the guinea pig maximisation test and the Buehler test (13). The LLNA (TG 429) and the two non-radioactive modifications, LLNA: BrdU-ELISA (TG 442 B) and LLNA: DA
Jun 26, 2009 The details of the validation of the LLNA and a review of the. 15 associated work have been published (6)(7)(8)(9)(10). Test Guideline 406 utilises guinea pig. 16 tests, notably the guinea pig maximisation test and the Buehler test (11). 17. 2. The LLNA: DA was developed as a nonradioactive modification to
Dec 15, 2009 Guideline to be promulgated for assessing skin sensitisation potential of chemicals in. 15 animals. Test Guideline 406 utilises guinea pig tests, notably the guinea pig maximisation. 16 test and the Buehler test (10). The LLNA: BrdU-ELISA provides certain advantages over TG. 17. 406 with regard to both
Jul 22, 2010 OECD Guidelines for the Testing of Chemicals are periodically reviewed in light of scientific provided there is adherence to all other LLNA protocol specifications, as described in this Test Guideline. limitations that may necessitate the use of TG 406 (13) (e.g. false negative findings in the LLNA with.
Aug 1, 2017 lymph node assay (TG 429). This Test Guideline is designed for assessing skin sensitisation potential of chemicals in animals. TG 406 utilises guinea pig tests, notably the guinea pig maximisation test and the Buehler test (13). The LLNA (TG 429) and the non-radioactive modifications, LLNA: BrdU-.
lymph node assay (TG 429). This Test Guideline is designed for assessing skin sensitization potential of chemicals in animals. TG 406 utilises guinea pig tests, notably the guinea pig maximisation test and the Buehler test (13). The LLNA (TG 429) and the two non-radioactive modifications, LLNA: BrdU-ELISA and FCM (TG
Apr 24, 2002 the second Guideline to be promulgated for assessing skin sensitisation potential of chemicals in animals. The other Guideline (406) utilises guinea pig tests, notably the guinea pig maximisation test and the. Buehler test (4).. 2. The LLNA provides certain advantages with regard to both scientific progress

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March 2018