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3 Apr 2012 E.g. repeated doses of carbamazepine induce the enzymes responsible for its elimination (ie, auto-induction) Auto- inhibition may occur during the course of metabolism of certain drugs CLASSIFICATION OF TIME DEPENDENT PHARMACOKINECTICS Physiologically induced time dependency
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chronopharmacokinetics - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. Chronopharmacokinetics P Physiologically-induced time dependency. P Chemically-induced time dependency www.bpharmstuf.com. Physiologically-induced time dependency:
3 Oct 2012 Introduction: : Introduction: Absorption, distribution, metabolism and elimination are influenced by many different physiological functions of the body which may vary with time of day. The rate of absorption and elimination of a drug, changes in cyclical (24 hr interval) or in a non cyclical (longer period of time)
Time dependent Pharmacokinetics: Introduction, classification, physiologically induced time dependency: Chrono Pharmacokinetics. 8. Clinical Pharmacokinetics: Altered kinetics in pregnancy, child birth, infants and geriatrics, liver, and renal diseased states. Practicals: Based on Theory. II- PHARMACEUTICAL
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22 Aug 2014 b) Chemically induced time dependency Auto induction Induction of enzymes by the drug is responsible for elimination there by increase the clearence of the drug. Ex: repeated doses of carbamazepine, rifampicin induces the enzymes responsible for their elimination. 2) Auto inhibition The metabolites

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February 2018