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12 Apr 2017 Summary. Recent trials suggest procalcitonin-based guidelines can reduce antibiotic use for respiratory infections. However, the accuracy of procalcitonin to d. Systematic pathogen testing included cultures, serology, urine antigen tests, and molecular detection. Accuracy of procalcitonin to discriminate
10 Nov 2016 Procalcitonin-Guided Evaluation and. Management of Lower *IDSA: includes recommendations from Surviving Sepsis Campaign and SHEA . Difficult to compare studies. • Evaluate impact of diagnostic on patient management and outcomes. • May not be able to determine accuracy of test. • Variable.
7 Dec 2016 The recent stop antibiotics on procalcitonin guidance study (SAPS), the largest procalcitonin trial to date, demonstrated reduction in both antibiotic exposure and mortality in critically ill Several different procalcitonin assays exist, but all demonstrate good concordance at clinically relevant cutoffs [9].
13 Apr 2016 IDSA FEATURES. Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology Evidence-based guidelines for implementation and measurement of antibiotic stewardship interventions in inpatient populations in-.
8 Dec 2017 Stanford T. Shulman, MD, outlines reasons why IDSA elected not to endorse the 2016 Surviving Sepsis Campaign Guidelines. therapy.4 IDSA also criticizes the SSCG for endorsing the use of procalcitonin levels for diagnosis without providing specific and evidence-based guidance, and also for failure to
11 Dec 2017 Members of the IDSA Sepsis Task Force stated in the paper that their perspectives and interpretations of major studies the guidelines are based on. provide more specific guidance on the use of biomarkers, specifically procalcitonin, and molecular tests to identify pathogens and guide treatment decisions;
the promise of emerging diagnostics, IDSA presents recommendations that address a host of identified barri- ers. Achieving these Keywords. diagnostics; rapid diagnostics; point-of-care testing; molecular diagnostics; clinical microbiology; infectious increased interest in biomarkers; procalcitonin (PCT) is a promising
24 Feb 2017 The US Food and Drug Administration (FDA) has cleared the expanded use of the Vidas Brahms procalcitonin (PCT) test to help clinicians determine whether antibiotic treatment should be initiated or stopped in patients with lower respiratory tract infections and stopped in patients with sepsis. The Vidas
To test if an algorithm based on serial measurements of procalcitonin (PCT) allows reduction in the duration of antibiotic therapy compared with empirical rules, and does not result in more adverse outcomes in patients with severe sepsis and septic shock. Design. • Single center, randomized, controlled, open interventional
1 Jun 2012 IDSA GUIDELINES. 2012 Infectious Diseases Society of America. Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infections a. Benjamin A. .. testing of a wound specimen as well as the patient's clinical CRP and procalcitonin, especially when these values were com- bined

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February 2018