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For most methods, this decision rule controls the familywise error rate at or below the level. However, the false discovery rate controlling procedures control the false discovery rate at or below the level. PROC MULTTEST provides the following p-value adjustments: Bonferroni. Sidak. step-down methods. Hochberg. Hommel.
of intersection tests which . . . – . . . is more explicit in terms of the quantities to be computed,. – . . . still covers most examples from the literature,. – . . . allows to derive a shortcut also in cases of logical constraints, e.g. for the all pairwise- comparison closed test procedure of HOMMEL & BERNHARD (1999). 12
Sep 20, 2013 Alex Dmitrienko [Multiple Testing Procedures in Clinical Trials]. Slide 76. Semiparametric procedures. Based on univariate p-values. Some distributional assumptions. Examples: Hochberg and Hommel procedures. Properties. Perform better in problems with strongly correlated test statistics. More powerful
Westfall and Wolfinger (2000) note that several of the methods available in PROC MULTTEST are closed—namely, the step-down methods, Hommel's method, and This process is repeated a large number of times, and the proportion of resampled data sets where the minimum pseudo-p-value is less than or equal to an
Examples are given of adjusted P—values for multiple comparisons in the analysis of variance and of adjusted P—values based on the Bonferroni procedure and modi?cations of that procedure by Holm (1979, Scandinavian. Journal of Statistics 6, 65—70), Hochberg (1988, Biometrika 75, 800—802), and Hommel (1988,.
This presentation revisits the Closure Principle of Marcus, Peritz, and Gabriel (1976) and its implementation by most multiple testing procedures, which I will show to be sometimes conservative. Discuss a simple example of a test procedure that follows the original as well as a typical conservative implementation. Present a
testing procedure. Introduction. The area of multiple comparisons and multiple testing has been seemingly taken over with. "closed testing" applications in recent documentation for PROC GLM, (See SAS/STAT User's Guide, Version 8, Volumes 1, 2, and 3), T2 test (refer, for example, to Johnson and Wichern, 1998, p.
Feb 6, 2011 The Hommel procedure defined in Section 2.6.8 is an example of a nonconsonant closed testing procedure. It is possible for this procedure to reject the global null hypothesis HI, I = {1,,m}, without rejecting any other intersection hypotheses. ?-exhaustive procedures. An ?-exhaustive procedure is a closed
Hommel. Fisher combination bootstrap permutation adaptive methods false discovery rate positive FDR. The Bonferroni and Sidбk adjustments are simple functions of Getting Started: MULTTEST Procedure. Drug Example. Suppose you conduct a small study to test the effect of a drug on 15 subjects. You randomly divide.
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