Reordering Life: Knowledge and Control in the Genomics Revolution (Inside Technology)
by Stephen Hilgartner
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The rise of genomics engendered intense struggle over the control of knowledge. In Reordering Life, Stephen Hilgartner examines the "genomics revolution" and develops a novel approach to studying the dynamics of change in knowledge and control. Hilgartner focuses on the Human Genome Project (HGP) -- the symbolic and scientific centerpiece of the emerging field -- showing how problems of governance arose in concert with new knowledge and technology. Using a theoretical framework that analyzes "knowledge control regimes," Hilgartner investigates change in how control was secured, contested, allocated, resisted, justified, and reshaped as biological knowledge was transformed. Beyond illuminating genomics, Reordering Life sheds new light on broader issues about secrecy and openness in science, data access and ownership, and the politics of research communities.
Drawing on real-time interviews and observations made during the HGP, Reordering Life describes the sociotechnical challenges and contentious issues that the genomics community faced throughout the project. Hilgartner analyzes how laboratories control access to data, biomaterials, plans, preliminary results, and rumors; compares conflicting visions of how to impose coordinating mechanisms; examines the repeated destabilization and restabilization of the regimes governing genome databases; and examines the fierce competition between the publicly funded HGP and the private company Celera Genomics. The result is at once a path-breaking study of a self-consciously revolutionary science, and a provocative analysis of how knowledge and control are reconfigured during transformative scientific change.
Reordering Life: Knowledge and Control in the Genomics Revolution (Inside Technology) Stephen Hilgartner
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《Medicine, Health Care and Philosophy》 - 2009 - 被引量:15The exponential increase in knowledge, the genomics, proteomics and computing ...use the vast resources that the genomics revolution and computational speeds ...Their contributions focus on African ways of looking, meaning-making, and creating Reordering Life Knowledge and Control in the Genomics Revolution By ...Discover the world's research 12+ million members 100+ million publications 700k+ research projectsJoin for free...2016年12月19日 - _thelivesofmysistersandeveryonearoundme.In55_myself...andsuddenlyIfeltsomethinginsideonepillow.Itwassmall...ofExcellenceforKangarooGenomicss...the π-calculus, SCIENCE IN CHINA (Series E),...and unlabelled ones[J].BMC Genomics 2010,11(...An Integrated Reordering Model for Statistical Machine...: Evolutionary Transients in the Rice Transcriptome...Genomics, Proteomics & Bioinformatics 2010 8 (4)...and application of automation control system to ...Genomics Received: 23 September 2014 Accepted: 29...1a, lower middle and right panels)Peter , Chika B 79c7fb41ad
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