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A discussion of the teratogenicity of antiepileptic drugs (AEDs) may be found elsewhere.4 In general, women who take AEDs have double the risk of bearing a
the limited data on the newer AEDs and studies linking neurocognitive outcomes to AED exposure. During pregnancy, important considerations include
lamotrigine levels during pregnancy can result in aggravation of seizures in some women.9. Measurement of total plasma concentration for most AEDs is
during pregnancy, delivery and in the immediate post partum period. WWE should be counselled about the dangers of abruptly stopping their seizure medication
AND SAFETY DUrING PrEGNANCY. I have epilepsy and plan to become pregnant. Will taking an AED during pregnancy put me at risk for a difficult pregnancy?
21 Jun 2016 Women with epilepsy are classified as high risk during pregnancy, and on the taking of antiepileptic drugs (AEDs) in pregnancy, stating that
PREGNANCY: The lowest effective dose of the most appropriate AED should be used, aiming for monotherapy where possible. Recent pregnancy databases have suggested that valproate is significantly more teratogenic than carbamazepine, and the combination of valproate sodium and lamotrigine is particularly teratogenic.
WWE who are planning their pregnancy should have a clinician competent in the management of epilepsy take responsibility for sharing decisions around choice and dose of AEDs, based on the risk to the fetus and control of seizures.
Part of this guideline covers the recommended anti-epileptic drugs (AEDs) for treating Cautions: be aware of potential effect of sodium valproate in pregnancy
20 Jan 2016 Management of psychotropic drugs during pregnancy Exposure to Anti-Epileptic Drugs (AEDs) in Pregnancy: Importance of clinical indication
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