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This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant
30 Mar 1989 Pow is a key parameter in studies of the environmental fate of chemical substances. A highly-significant relationship between the Pow of substances and their bioaccumulation in fish has been shown. It has also been shown that Pow is a useful parameter in the prediction of adsorption on soil and
2 Oct 2012 Environmental fate and behaviour. The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals.
14 Jun 1996 In the Detailed Review Paper on Bioaccumulation prepared by Japan (February 1990), it was recommended that the existing five Guidelines for bioaccumulation, 305A to E, be consolidated into a single method. At the same time, work was proceeding on the updating of Guideline 305 E, Flow-through Fish
2 Oct 2012 This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are permissible). Independent of the chosen exposure method, the
The Guidance on information requirements and chemical safety assessment (IR&CSA), Chapter R.7c: Endpoint specific guidance (November 2012, version 1.2) refers to the draft of OECD test guideline 315. A number of specific considerations are listed which should be considered when interpreting results of
1 Dec 2011 (e) Substance stability in food (specifically when a dietary exposure test approach is chosen); Independent of the chosen exposure method or sampling scheme, this guideline describes a procedure for characterising the bioaccumulation potential of substances in fish.
Tools for Modeling Bioaccumulation Potential in Fish: Zip file: This file contains models to be implemented for both aqueous and dietary experimental exposure of chemicals to fish, as proposed in OECD Test Guideline 305. Estimation of uptake and depuration rate constants, growth correction, kinetic BCF and BMF, lipid
12 Apr 2016 The aim of this document is to give guidance to the experimenter and user of the bioconcentration or bioaccumulation data on how to perform the test, calculate the results and interpret them. This guidance document should be seen as an explanation to the revised test guideline, not as a substitute for it. 3.
A revised version of the OECD 305 test guideline (TG) was published in 2012 following a revision led jointly by chemical regulators from Germany, the Netherlands and the UK. The main changes in the revised TG were: • incorporation of a dietary bioaccumulation test suitable for determining the bioaccumulation potential of

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January 2025