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The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS.
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Authors: Okamoto I, Kawano Y, Matsumoto M, Suga M, Kaibuchi K, Ando M, Saya H; Journal: J Biol Chem (1999) 274:25525-25534; PubMed ID: 10464284. Catalog #. R415 The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis. Authors: Durr J . Manual / Product Insert
Previous characterization of the Saccharomyces cerevisiae Spt4, Spt5, and Spt6 proteins suggested that these proteins act as transcription factors that modify chromatin . Both of these amino acid changes occur between regions G and H of Rpb1, two of the eight blocks of sequence homology conserved among the largest
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