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Therapy of lymphoblastic lymphoma (LL) has evolved with use of chemotherapy regimens modeled after those for acute lymphocytic leukemia (ALL). We treated. 33 patients with LL with the intensive chemotherapy regimens hyper–CVAD. (fractionated cyclophosphamide, vincris- tine, Adriamycin, and dexamethasone) or.
CNS prophylaxis: • Patients with ALL, Burkitt's, Lymphoblastic lymphoma, and other aggressive NHL patients per MD discretion are to receive IT chemotherapy with each cycle. • If CNS is positive at diagnosis, then twice weekly lumbar punctures with intrathecal chemotherapy until negative times two, then per protocol.
See rituximab recording chart, page 4. •. Encourage patients to drink at least 3 litres of fluid per day, and to void frequently when receiving cyclophosphamide. •. Hyper CVAD consists of 2 regimes – Hyper CVAD and High dose Methotrexate and Cytarabine Arabinoside. A full cycle consists of both regimes given 21 days
Your doctor or nurse clinician has prescribed for you a treatment called Hyper-CVAD which contains the drugs: cyclophosphamide, vincristine, doxorubicin (also known as. Adriamycin. ®. ) and dexamethasone which is a steroid. Hyper-CVAD treatment also includes methotrexate and cytarabine which alternate with the
7 Dec 2011 programme that combined rituximab with HyperCVAD regimen (hyperfractionated cyclophsophamide, vincristine, doxorubicin, dexamethasone) alternating with high dose. (HD) Ara-C and HD-methotrexate (R-HCVAD-AM). The. 87% complete response (CR) rate and the 82% 3-year overall survival (OS)
26 Jul 2010 Purpose. The adverse prognosis of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia (ALL) prompted incorporation of monoclonal antibody therapy with rituximab into the intensive chemotherapy regimen hyper-CVAD (fractionated cyclophosphamide, vincristine,
1.13 Hyper-CVAD/MA. Indication. •. Mantle-cell lymphoma (diffuse, nodular or blastic variants). •. Hyper-CVAD/MA has also been used in adult B-cell Acute. Lymphoblastic Leukaemia. •. Relapsed lymphomas. •. Burkitt's Lymphoma. Pre-treatment Evaluation. •. Document histological sub-type of lymphoproliferative disorder
24 Feb 2006 METHODS. To evaluate the addition of rituximab, a CD20 monoclonal antibody, to intensive chemotherapy in adults with BL or B-ALL, 31 patients with newly diag- nosed BL or B-ALL received the hyper-fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (hyper-CVAD) regimen
R'HCVAD in a similar population. have been treated on this clinical trial. Aalglminttzd B'th m combmatlon developed a hyper-CVAD and nelarabine regimen where two cycles of nelarabine are given during Among patients 60 years or older with ALL, hyper—CVAD chemotherapy results in a CR rate of 80%, but the
Antiretroviral-Chemotherapy Interactions: Hyper CVAD regimen after chemotherapy). The authors concluded that hyper-CVAD was highly effective within this context. Although no direct comparisons between patients receiving cART and those . Vaccher E, Spina M, di Gennaro G, Talamini R, Nasti G, Schioppa O, et al.
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