CPEB3 ribozymes using a structure-based template, they
Sep 18, 2015 Hatchet RNAs are members of a novel self-cleaving ribozyme class that was . For example, Ht-2 ribozyme self-cleavage assays revealed that
Jan 31, 2017 Small self-cleaving ribozymes have been discovered in all evolutionary .. Other self-cleaving ribozyme examples that have guanosine as the
Oct 15, 2015 Self-cleaving ribozymes were discovered 30 years ago, but their Other examples, including highly conserved mammalian ribozymes, suggest

Apr 24, 2017 self-cleaving ribozymes, termed twister, twister sister, pistol, and hatchet By definition, a pseudoknot is a nucleic acid secondary structure that
Oct 15, 2015 It is the only example of a metabolite-responsive self-cleaving ribozyme, utilizing glucosamine 6-phosphate (glcN6P) as a cofactor necessary for catalysis.
Ribozymes (ribonucleic acid enzymes) are RNA molecules that are capable of catalyzing . For example, in self cleaving ribozyme RNAs, an in-line SN2 reaction is carried out using the 2' hydroxyl group as a nucleophile attacking the bridging
Self-cleaving ribozymes were discovered 30 years ago, but their biological distribution Other examples, including highly conserved mammalian ribozymes
Nov 17, 2013 In contrast, DNA templates with mutations in highly conserved nucleotides yielded products that matched the sizes expected for uncleaved RNAs. These results indicated that at least some of the conserved nucleotides among twister RNAs are important for self-cleaving ribozyme function.

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August 2017