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6 days ago Full-text (PDF) | An ulcer is disease of epithelial cells of body or organ which represents an open sore in the lining of epithelial cells or deep lesion in the specific region resulting into its degradation thus disrupting the normal physiology of the organ affected. The damage can be to the exte
lation and cellular mechanisms of acid secretion; (2) to classify drugs used in ulcer therapy according to their sites and mechanisms of action; (3) to discuss the important drugs with respect to their phar- macokinetics, clinical efficacy, and side effects; and (4) to provide a perspective for use of the various agents in peptic
Erosion or Mucosal ulceration occurs when the aggressive factors. Acid. Pepsin. Overwhelm. Bile the defensive factors (mucus, bicarbonate, PGS, blood flow and the process of regeneration after cellular injury). 99% of peptic ulcer is caused by the infection with Helicobacter pylori or by non-steroidal anti inflammatory drugs.
Pharmaceutical markets are usually bounded in terms of therapeutic classes of drugs, the members of which are substitutes. Thus it is important to distinguish between consumption externalities at two levels. The first is with respect to a therapeutic class, e.g., H2-antagonist antiulcer drugs, SSRI antidepressants,
Antacids and other antiulcer drugs. Antacids (usually containing aluminium or magnesium compounds) can often relieve symptoms in ulcer dyspepsia and in non-erosive gastro-oesophageal reflux; they are also sometimes used in non-ulcer dyspepsia but the evidence of benefit is uncertain. Antacids are best given when
both clinical and epidemiological, indicates that drug-induced achlorhydria is unlikely to be a problem in humans. Site protective agents have a role in certain conditions such as pregnancy where the systemic effect of a drug may produce adverse effects. 121. 1. Classification of Antiulcer Drugs. Antiulcer drugs fall into 4
overeating. 4. Smoking and excessive alcohol are direct causes of increased morbidity. 5. Drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) and painkillers for rheumatism irritate and damage gastric mucosa. Classification of the Drugs. Drugs for peptic ulcers are mainly classified into the following categories: 1.
6 Feb 2013 Anti ulcer drugs classification. 1. Anti-ulcer DrugsZulcaif Ahmad; 2. Introduction Peptic /stomach ulcer is the condition in which imbalance of aggressive factor and defensive factors. From ancient time stomach ulcer has been recognized and also therapy established according to their knowledge.
Classification of antiulcer drugs1.Reduction of gastric acid: a) H2 Anti Histamines: Cimetidine Ranitidine Pantaprazole b) Proton Pump Inhibitors
Review of Antiulcer Drugs. Aluminum hydroxide. Antiulcer. Antacid. Atropine. Anticholinergic. Antimuscarinic Treatment for bradycardia, diarrhea, cholinesterase poisoning. Azithromycin. Macrolide antibiotic. Bacteriostatic protein synthesis inhibitor. 50S ribosome. Inhibits translocation. Bismuth subsalicylate. Antiulcer
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