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Corticobasal degeneration (CBD) is a rare and progressive neurodegenerative disease. It was originally described as a dis- tinct clinicopathological entity in 19671 and later recognized as a polymorphous disease due to its complexity. In fact, the classical set of symptoms – namely asymmetric motor fea- tures associated
27 Dec 2017 Full-Text Paper (PDF) | 10.1590/s1980-5764-2016dn1004003 | Dementia e Neuropsychologia | Corticobasal syndrome (CBS) is an atypical parkinsonian syndrome of great interest to movement disorder specialists and behavioral neurologists. Although originally considered a primary motor disorder, it is
Summary. Corticobasal syndrome (CBS) is characterized by asymmetric involuntary movements including rigidity, tremor, dystonia, and myoclonus, and often associated with apraxia, cortical sensory deficits, and alien limb phenomena. Additionally, there are various nonmotor. (cognitive and language) deficits. CBS is
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations. An international consortium of behavioral neurology, neuropsychology, and movement disorders specialists developed
ABSTRACT: Corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP) represent chal- lenging neurodegenerative disorders for clinicians and nonclinical scientists alike. Although initially lumped together as “Parkinson's-Plus" syndromes, CBS and. PSP are clinically and pathologically distinct from Par-.
Patients with corticobasal degeneration can present with several different clinical syndromes, making ante-mortem diagnosis a challenge. Corticobasal syndrome is the clinical phenotype originally described for corticobasal degeneration, characterized by asymmetric rigidity and apraxia, cortical sensory deficits, dystonia
Abstract. The corticobasal degeneration syndrome has been suggested to be part of a complex of conditions (including the different subtypes of frontotemporal dementia and progressive supranuclear palsy), which reflect a spectrum of pathological substrates. This concept is supported by the frequent clinical overlap that
Corticobasal syndrome (CBS) is a condition that causes changes in movement, language skills or both. CBS may start with movement problems, such as stiff muscles on one side of the body involving the arm, leg, or both. People with CBS may describe having a hard time controlling their arm or leg. Some people with CBS
8 Dec 2010 Introduction and history. While historical review suggests earlier reports of the entity now known as corticobasal degeneration (CBD), the disease was first clearly described in a series of three cases in. 1968, when it was termed corticodentatonigral degeneration with neuronal achromasia. [ 1 ]. Subsequent
Corticobasal Degeneration. The Syndrome and the Disease. Bradley F. Boeve. INTRODUCTION. In 1967, Rebeiz, Kolodny, and Richardson described three patients with a progressive asymmetric akinetic-rigid syndrome and apraxia and labeled these cases as “corticodentatonigral degeneration with neuronal achromasia"
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