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haemolytic anaemia ppt
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intracorpuscular hemolytic anemia definition
intracorpuscular hemolysis definition
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Unit 16: Extracorpuscular Defects: Immune and Nonimmune. Hemolytic Anemia. Learning Objectives. At the end of this unit, the student should be able to: 1. Describe the mechanism of immune intravascular and extravascular hemolysis. 2. List lab tests useful diagnosis of immune hemolytic anemia. 3. List 3 classifications
APPROACH TO DIAGNOSIS. An essential feature of hemolytic anemia is a reduction in the normal red cell sur- vival of 120 days. Premature destruction of red cells may result from corpuscular abnormalities (within the red cell corpuscle), that is, abnormalities of membrane, enzymes, or hemoglobin; or from extracorpuscular
9 Mar 2014 Pathology. Reappraisal of the Etiology of Extracorpuscular Non-Autoimmune Acquired. Hemolytic Anemia in 2657 Hospitalized Patients with Non-Neoplastic Disease. Victor C. Kok1,2, Chien-Kuan lee3, Jorng-tzong horng1,4, Che-Chen lin5 and Fung-Chang sung6. 1Department of Biomedical Informatics,
Hemolytic Anemia. Key Points: •. Think of hemolytic anemia as intracorpuscular vs. extracorpuscular. •. Coombs' positivity = immune-mediated hemolysis; the pattern of the Coombs' (IgG vs. C3) can be useful. I. Etiology: Many different ways of classifying (intra- v. extravascular, acquired v. hereditary) – this is probably.
HEMOLYTIC ANEMIA. Causes. ? INTRACORPUSCULAR HEMOLYSIS. ? INTRACORPUSCULAR HEMOLYSIS. ? Membrane Abnormalities. ? Metabolic Abnormalities. ? Metabolic Abnormalities. ? Hemoglobinopathies. EXTRACORPUSCULAR HEMOLYSIS. ? EXTRACORPUSCULAR HEMOLYSIS. ? Nonimmune.
Anand Lagoo/Hereditary Anemias RS/5-12. Classification of Hemolytic anemias 2. ? Extracorpuscular factors. ? Immune hemolytic anemias. ? Autoimmune hemolytic anemia. ? Transfusion of incompatible blood. ? Nonimmune hemolytic anemias. ? Chemicals. ? Bacterial infections, parasitic infections (malaria),
I. BLOOD LOSS: a. acute: traumatic shock, b. chronic: gynecological or gastrointestinal diseases. II. HEMOLYTIC ANEMIAS: a. intrinsic (intracorpuscular) abnormalities: 1. abnormalities of cytoskeleton,. 2. enzyme deficiencies,. 3. disturbances of hemoglobin synthesis. b. extrinsic (extracorpuscular) abnormalities: 1. antibody
9 Oct 2015 (extracorpuscular) defects.2–4 It is important to mention that most intrinsic defects are inherited, and most extrinsic ones are acquired,2 however, there are some exceptions to this rule. For example, paroxysmal nocturnal hemoglobinuria (PNH) is an acquired HA produced by an intrinsic defect4 and glucose
On Dec 31, 2016, Lawrence C. Wolfe published the chapter: Extracorpuscular Hemolytic Anemia in the book: Lanzkowsky's Manual of Pediatric Hematology and Oncology.
Sickle cell anemia. (c) Abnormalities of red cell enzymes – eg. G6PD deficiency. 18.4.2 Defects outside the RBC (Extracorpuscular defects). The red cells are normal but the life span is shortened because of external factors. (a) Immune hemolytic anemia- alloimmune, autoimmune, drug induced. (b) Parasites – eg. Malaria.
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