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Background: Thiazide-induced hyponatraemia is common and potentially life threatening. In the absence of well-defined risk factors for this compli- cation, guidelines for prescribing cannot be estab- lished. Aim: To examine whether a subgroup of patients is particularly susceptible to this complication. Design: Retrospective
Diuretic-induced Severe Hyponatremia*. Review and Analysis of 129 Reported Patients. Moshe Sonnenblick, M.D.; Yechiel Friedlander, Ph.D.; and. Arnold J Rosin, M.B.. Thiazides were responsible for severe diuretic-induced hyponatremia (serum sodium level < ll5 mEqiL) in 94 percent of 129 cases reported in the
30 Jun 2010 Virtually all cases of severe diuretic-induced hyponatremia have been due to a thiazide-type diuretic6-12). In contrast, loop diuretics are implicated much less commonly7). Thiazide diuretics inhibit NaCl reabsorption in the distal convoluted tubule, the main diluting site of the nephron.
Thiazide-Induced Hyponatremia Associated with. Death or Neurologic Damage in Outpatients. NASIM ASHRAF, M.D.. RICHARD LOCKSLEY, M.D.. ALLEN I. ARIEFF, M.D.. San Francisco, California. From the Nephrology Section, Department of. Medicine, Veterans Administration Medical. Center and the University of
18 Dec 2017 Full-text (PDF) | The importance of thiazide-induced hyponatremia (TIH) is reemerging because thiazide diuretic prescription seems to be increasing after the guidelines recommending thiazides as first-line treatment of essential hypertension have been introduced. Thiazide diuretics act by inhibiti
A SUSPECTED CASE OF THIAZIDE-INDUCED HYPONATREMIA by Charles D. Ponte. THE SYNDROME of inappropriate antidiuretic hormone secretion (SIADH) is characterized by hyponatremia associated with an adequate circulation and an expanded extracellular fluid volume. Hyponatremia in the presence of urinary
Thiazide diuretics are associated with an increased risk of hyponatremia. The aim of this study was to investigate possible predictors of thiazide-induced hyponatremia. A total of 48 patients admitted to the ward or to the emergency department due to severe thiazide-induced hyponatremia (Na < 125 mmol/L) were enrolled in
is recommended that thiazides be avoided in elderly frail patients with chronically high water intake, in patients who have psychogenic polydipsia, and heavy beer drinkers, as these patients depend on excretion of maximally dilute urine to maintain fluid balance.3,4. Thiazide-induced hyponatremia is linked to increased.
6 Feb 2016 Abstract. Thiazide-induced hyponatremia is one of the main causes of decreased sodium levels in elderly individuals. This review presents the current evidence regarding the thiazide-associated hyponatremia. Thiazide-associated hyponatremia is observed mainly in patients with cer- tain risk factors such
Thiazide-Induced Hyponatremia Associated with. Death or Neurologic Damage in Outpatients. NASIM ASHRAF, M.D.. RICHARD LOCKSLEY, M.D.. ALLEN I. ARIEFF, M.D.. San Francisco, California. From the Nephrology Section, Department of. Medicine, Veterans Administration Medical. Center and the University of
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