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Chicken Enucleated Eye Test (CEET). 3.2. 6. Future prospects and recommendations for achieving animal replacement. 7.References to OECD TG 405 (OECD, 2002), where the in vivo rabbit eye test needs only to be performed as a last
2 Jan 2015 The IRE test, or rabbit enucleated eye test (REET) was originally This guidance was adopted in 2009 (OECD, 2009a) and updated in 2013
Chicken Enucleated Eye Test or the Isolated Chicken Eye test (CEET or ICE). 2. Internationally, the OECD published their first guideline on eye irritation in
26 Jul 2013 OECD GUIDELINES FOR THE TESTING OF CHEMICALS for the in vivo rabbit eye test, the ICE test method is recommended as an . The enucleated eye is mounted in a stainless steel clamp with the cornea positioned.
7 Sep 2009 rabbit eye test, the BCOP is recommended for use as part of a . The OECD is developing a Guidance Document on the use of in vitro ocular damage to the eyes, the eyes should be enucleated as soon as possible after
18 Dec 2008 Patric.amcoff@oecd.org. 1 complete replacement for the in vivo rabbit eye test, the ICE is induce toxicity in an enucleated chicken eye.
2 Dec 2015 Keywords: eye irritation, Draize eye test, OECD guideline, corneal equivalent eye; IRe; isolated rabbit eye; OeCD; Organisation for economic Co-operation and Development; . Enucleated eyes are assessed for corneal in-.
2 Oct 2012 OECD Guidelines for Testing of Chemicals are periodically reviewed to . an opening the size of a rabbit eye placed directly before the paper.

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March 2018