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Abstract. Peptides act as vasoconstrictors (for instance angiotensins, vasopressin) or vasodilators (the kinins, the neurokinins), both through direct activation of specific receptors in the vascular smooth muscles or indirectly through the release of other endogenous inhibitors of the vascular tone. Kinins and neurokinins as
Request (PDF) | Importance of endoge | The magnitude of the clinical benefits produced by inhibitors of the renin-angiotensin system in heart failure has been modest, possibly because of the ability of renin-angiotensin activity to escape from suppression during long-term treatment. Efforts to intensify pharmacological
Introduction. Endogenous peptides, such as vasoactive intestinal polypeptide (VIP), C-type natriuretic peptide. (CNP), and bradykinin (BK), have been proposed to play a role in the female sexual arousal response by exerting relaxation of clitoral, labial, and vaginal smooth muscle. While the effects of endogenous peptides
The better-known vasoactive peptides include angiotensin, bradykinin, natriuretic peptides, calcitoningene-related peptide (CGRP), endothelin, neuropeptide Y (NPY), substance P and vasoactive intestinal peptide (VIP) (discussed in this chapter), and vasopressin (Chapters 15 and 37). Many other endogenous peptides
1. Vasoactive peptides and drugs. Prof. Dr. Oner Suzer www.onersuzer.com osuzer@istanbul.edu.tr. Last update: 28.12.2010. 22. Vasoconstrictors and vasodilators
2 Dec 2016 Importance of endogenous compensatory vasoactive peptides in broadening the effects of inhibitors of the renin-angiotensin system for the treatment of heart failure. Milton Packer, John J V McMurray. The magnitude of the clinical benefits produced by inhibitors of the renin-angiotensin system in heart
It causes vasodilation, hypo- tension, peripheral cyanosis, and increased vascular permeability in anesthetized rats. In dogs, however, neurotensin is a systemic vasoconstrictor.18. The chemically related amphibian peptide, xenopsin, is also vasoactive. Opioid Peptides. The endogenous opioid peptides, including endor-.
20 Dec 2017 Request (PDF) | Endogenous Vasoactiv | Introduction. Endogenous peptides, such as vasoactive intestinal polypeptide (VIP), C-type natriuretic peptide (CNP), and bradykinin (BK), have been proposed to play a role in the female sexual arousal response by exerting relaxation of clitoral, labial, and
ment of endogenous vasoactive peptides in a variety of other physiological activities, in- cluding pain transmission, behavioral actions, and metabolic processes. Vasoactive peptides have been shown to play an important role in many pathological situations, for example, asthma, arthritis, vascular headaches, hyper- tension
The study of vasoactive peptides is of significant interest and potential at the present time. In recent years, many endogenous vasoactive peptides have been isolated and characterized several of which are involved in the regulation of the cardiovascular and body fluid homeostasis. Some of these peptides, such as
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