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DNA Sequencing & The Human Genome. Project. An Endeavor Revolutionizing Modern Biology. Jutta Marzillier, Ph.D. Lehigh University. Biological Sciences. November 13th , 2013
491-495. Human Genome Project. Goals: ? identify all the approximate 30,000 genes in human DNA,. ? determine the sequences of the 3 billion chemical base pairs that make up human DNA,. ? store this information in databases,. ? improve tools for data analysis,. ? transfer related technologies to the private sector,
Genomics and the Human Genome Project. Learning goals. By the end of this material you should have learnt about: The genome of an organism i.e. the structure and function of an organism's genetic material. The purpose and function of the human genome project. Graphical representations of the chromosomes that
Human Genome Project – Approach Used. Concept. Produce ever more detailed maps of chromosomes; 1. Genetic linkage map (low resolution). Relative order & spacing of disease linked genes (not physical map). 2. Combine with STS/EST (sequence tag site/ expressed sequence tag) maps. Position of unique DNA
3. Genome Project Goals (1). • Obtain physical map of genome. – Allows rough location of genetic fragments. • Develop sequencing technology. – Increase throughput and reduce cost. • Obtain human DNA sequence. – Achieve high accuracy, make freely accessible. • Analyze human sequence variation. – Identify SNPs
23 May 2012 www.google.com/img res?q=human+genome+proj ect&hl=en&safe=active&gbvThe Human Genome Project Bailey Paschal Bell: 3.
The Human Genome Project. • Brief History of the Human Genome Project. • Physical Chromosome Maps. • Genetic (or Linkage) Maps. • DNA Markers. • Sequencing and Annotating Genomic DNA. • What Have We learned from the HGP? • Identification of Disease Genes. • Use of Genomics for Individualized Medicine.
THE HUMAN GENOME PROJECT AND ITS. ETHICAL, LEGAL AND SOCIAL IMPLICATIONS. Tim Williams. Science and Technology Division. 26 July 2000. PARLIAMENTARY RESEARCH BRANCH. DIRECTION DE LA RECHERCHE PARLEMENTAIRE. PRB 00-08E
goals (1998-2003). – identify the approximate 100,000 genes in human. DNA. – determine the sequences of the >3 billion bases that make up human DNA. – store this information in databases. – develop tools for data analysis. – address the ethical, legal, and social issues that arise from genome research
Human Genome Project. ,ncG-CTA TGC TC TA. What is the Human Genome Project? The Human Genome Proiect [HGP] began in. 1990 when the U5. Nationai Institutes at Health and the Department at Energy ioined torces with internationai partners in a concerted ettort to determine the correct sequence ot a" three biiiion.
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